Responses of Nonhuman Primates to a Ol Brominatebdip Henyl Mixture

By Lambrecht, L. K.

Book Id: WPLBN0000115957
Format Type: PDF eBook
File Size: 0.8 MB
Reproduction Date: 2005

Title:	Responses of Nonhuman Primates to a Ol Brominatebdip Henyl Mixture
Author:	Lambrecht, L. K.
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Lambrecht, L. K. (n.d.). Responses of Nonhuman Primates to a Ol Brominatebdip Henyl Mixture. Retrieved from http://www.gutenberg.us/

Description
Government Reference Publication

Excerpt
Excerpt: Polybrominated biphenyls (PBBs) as an environmental contaminant were brought to public attention as a result of the accidental mixing of a commercial flame retardant, FireMaster (Michigan Chemical Corp., St. Louis, Michigan), into livestock feed in Michigan in July 1973 (I) . Affected dairy herds initially showed anorexia, with a 40% drop in milk production. Weight loss, lameness, and increased frequency of urination and excessive lacrimation were noted. Histologically, liver changes in the cattle included fatty metamorphosis and amyloidosis. There were also reports which indicated kidney changes including pigment nephrosis and acute, subacute and chronic interstitial nephritis. During pregnancy there was loss of appetite and leg weakness. At parturition weak or dead fetuses were common. Cows bred 4 to6 weeks prior cell disorders and neurological complaints 0, 4). Reproductive abnormalities in exposed women have not yet been fully evaluated. Studies show, however, that PBBs, like polychlorinated biphenyls (PCBs), affect steroidogenesis. Milk production, egg production, fertility and spermatogenesis have been found to be adversely affected in various species (2, 5, 6). In addition, PBBs have also been shown to pass across the placental barrier and be excreted in the milk of lactating mothers (7, 8). In order to determine the effects of PBBs on primates under controlled conditions, rhesus monkeys were fed diets containing PBBs at levels to which the human population may have been exposed. The data obtained in these experiments are the subject of this report. to PBB exposure returned to estrus (2).