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Environmental Health Perspectives, Vol. 31, Pp. 33-39, 1979 : Origin of Meiotic Non-Disjunction in Drosophila Females

By Grell, Rhoda. F.

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Book Id: WPLBN0000062027
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Reproduction Date: 2005

Title: Environmental Health Perspectives, Vol. 31, Pp. 33-39, 1979 : Origin of Meiotic Non-Disjunction in Drosophila Females  
Author: Grell, Rhoda. F.
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
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Publisher: United Nations- Office for Disarmament Affairs (Unoda)

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Grell, R. F. (n.d.). Environmental Health Perspectives, Vol. 31, Pp. 33-39, 1979 : Origin of Meiotic Non-Disjunction in Drosophila Females. Retrieved from http://www.gutenberg.us/


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Government Reference Publication

Excerpt
Excerpt: Most detectable aneuploidy in Drosophila, as well as in humans, occurs as a consequence of nondisjunction at the first meiotic division. In analyzing the origin of nondisjunctional gametes, one aspect frequently overlooked is the close dependence of nondisjunction on reduced chiasma frequency. Reductions arise either from decreased exchange or less often from premature chiasma resolution. Homologs that become univalents from either cause are expected to assort independently of one another and lead to the production of gametes carrying both or neither homolog one-half of the time. When univalent o ccur, some organisms, such as Drosophila, possess a mechanism to avert nondisjunction and its unfortunate consequences by providing a second opportunity for homologs to pair and disjoin regularlv. This mechanism is called distributive pairing (I)..

 
 



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