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Title: Bucladesine  
Author: World Heritage Encyclopedia
Language: English
Subject: List of MeSH codes (D13), Enoximone, Milrinone, List of drugs: Bs-Bz, CAMP-dependent pathway
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
sodium (3aR,4R,6R,6aR)-4-(6-butanamido-9H-purin-9-yl)-6-[(butanoyloxy)methyl]-2-oxo-tetrahydro-2H-1,3,5,2λ5-furo[3,4-d][1,3,2]dioxaphosphol-2-olate
Clinical data
CAS Registry Number  YesY
ATC code C01
PubChem CID:
ChemSpider  YesY
Synonyms • Dibutyryl cyclic adenosine monophosphate
• (N6,2'-O-dibutyryl)-adenosine-3',5'-mono-phosphate
• Dibutyryl cAMP
Chemical data
Formula C18H23N5NaO8P
Molecular mass 491.368 g/mol

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor.

Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations.

The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.

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