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Ubp-302

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Title: Ubp-302  
Author: World Heritage Encyclopedia
Language: English
Subject: Kainate receptor antagonists, Benzoic acids, Pyrimidines, Amino acids, A.C.E. mixture
Collection: Amino Acids, Benzoic Acids, Kainate Receptor Antagonists, Pyrimidines
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Ubp-302

UBP-302
Names
IUPAC name
2-{[3-[(2S)-2-amino-2-carboxyethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl]methyl}benzoic acid
Identifiers
 Y
Jmol-3D images Image
Properties
C15H15N3O6
Molar mass 333.296 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 Y  (: Y/N?)

UBP-302 is a highly selective kainate receptor antagonist used in the study of many neurological processes. It is active at micromolar concentration within an in vitro preparation and specifically targets the GluR5 subunit of the receptor. This compound was developed at the University of Bristol.[1]

References

  1. ^ More, JC; Nistico, R; Dolman, NP; Clarke, VR; Alt, AJ; Ogden, AM; Buelens, FP; Troop, HM; et al. (2004). "Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist". Neuropharmacology 47 (1): 46–64.  



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