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Worcester Foundation for Experimental Biology

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Title: Worcester Foundation for Experimental Biology  
Author: World Heritage Encyclopedia
Language: English
Subject: Combined oral contraceptive pill, Worcester, Massachusetts, Shrewsbury, Massachusetts, Gregory Goodwin Pincus, Asian American, Han Chinese, Hoagland-Pincus Conference Center, Luis E. Miramontes, V. Craig Jordan, Min Chueh Chang
Publisher: World Heritage Encyclopedia

Worcester Foundation for Experimental Biology

The Worcester Foundation for Biomedical Research (WFBR) was a non-profit biomedical research institute based in Shrewsbury, Massachusetts.[1][2]


The foundation was established as an independent research center under the name Worcester Foundation for Experimental Biology (WFEB) in 1944 by Hudson Hoagland and Gregory Pincus. It was best known for the development of the combined oral contraceptive pill by Pincus and Min Chueh Chang, an important development in modern birth control, and for pioneering research on in vitro fertilization by Chang. In the 1970s, WFEB scientists undertook the first systematic study of anti-tumor effects of the anti-estrogen tamoxifen led by 2003 Kettering Prize recipient V. Craig Jordan and initial studies of aromatase inhibitors by 2005 Kettering prize recipient Angela Brodie, two important classes of drugs to treat breast cancer.

Name change

In 1995, the name was changed to its current name to better reflect the increased focus on medical research. The institution ran into severe financial troubles and was taken over by the University of Massachusetts Medical School (UMMS) in 1997. The facility at 222 Maple Avenue, Shrewsbury, Massachusetts is currently operated by UMMS. The Hoagland-Pincus Conference Center at this site now hosts small scientific seminars, meetings, and retreats.[1][2]


External links

  • Chang, Min Chueh, "Recollections of 40 years at the Worcester Foundation for Experimental Biology" on PubMed

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