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Enoximone

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Title: Enoximone  
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Enoximone

Enoximone
Systematic (IUPAC) name
4-methyl-5-{[4-(methylsulfanyl)phenyl]carbonyl}-2,3-dihydro-1H-imidazol-2-one
Clinical data
AHFS/Drugs.com
Legal status
Routes of
administration
Intravenous
Pharmacokinetic data
Bioavailability 50% (oral)
Protein binding 85%
Metabolism Hepatic oxidation
Biological half-life 4 to 10 hours
Excretion Renal (60 to 70%)
Identifiers
CAS Registry Number  Y
ATC code C01
PubChem CID:
DrugBank  Y
ChemSpider  Y
UNII  Y
KEGG  Y
ChEMBL  Y
Chemical data
Formula C12H12N2O2S
Molecular mass 248.302 g/mol
 Y   

Enoximone (INN, trade name Perfan) is an imidazole phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure and is selective for phosphodiesterase 3.[1]

References

  1. ^ Boldt J, Suttner S (September 2007). "Combined use of ultra-short acting beta-blocker esmolol and intravenous phosphodiesterase 3 inhibitor enoximone". Expert Opin Pharmacother 8 (13): 2135–47.  


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