The objective of this article is to study the relationship between the symptomatology of Antisocial Personality Disorder (ASPD) and the levels of positive and negative affect in Mexican inmates. A sample of 65 male inmates was used, subsequently divided into 2 subsamples, one composed of 28 participants with probable ASPD and the other of 37, composed of inmates with high probabilities of not meeting the ASPD criteria. The diagnosis of ASPD was estimated based on the Aluja ETAPA scale, which assesses the presence of ASPD symptomatology, positive and negative affect was evaluated using the PANAS scales. Significant correlations were found between the ETAPA score and positive affect (low and negative) and negative affect (moderate and positive). In addition, inmates with probable ASPD showed a higher level of negative affect and less positive affect than the group with probable non-ASPD. The results obtained coincide partially with what was found in previous studies where psychopathy was evaluated. The present study supposes a first approximation on the relation between the positive and negative affects and the ASPD in Mexico....