Angiotensin-Converting Enzyme : Ii Pulmonary Endothelial Cells in Culture

By Ryan, Una S.

Book Id: WPLBN0000204133
Format Type: PDF eBook:
File Size: 1.22 MB
Reproduction Date: 2005

Title:	Angiotensin-Converting Enzyme : Ii Pulmonary Endothelial Cells in Culture
Author:	Ryan, Una S.
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago S. Rya, B. U. (n.d.). Angiotensin-Converting Enzyme : Ii Pulmonary Endothelial Cells in Culture. Retrieved from https://www.gutenberg.us/

Description
Government Reference Publication

Excerpt
Introduction: One of the technical limitations to progress in understanding of specific functions of a particular cell type is the availability of that cell type in pure culture. Over the past 12 years, a number of different specific metabolic activ-ities have been attributed to pulmonary endothelial cells. The cells can selectively process adenine nucleotides and biogenic amines (I, 2). In addition, endothelial cells are capable of forming prostaglandins such as PGE2 (3-5)a nd PGls (6, 7). Endothelial cells appear to have a great capacity for inactivating kinins and for converting angiotensin I into angiotensin 11 (3, 8), and in this sense endothelial cells of the pulmonary vascular bed can regulate the hormonal composition of sys- temic arterial blood. In addition, endothelial cells appear to possess a number of hemostatic factors including a*-macroglobulin (9). plasminogen activator (10) and factor VIlI antigen (I I).