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Tfiie

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Tfiie

general transcription factor IIE, polypeptide 1, alpha 56kDa
Identifiers
Symbol GTF2E1
Alt. symbols TF2E1
Entrez HUGO OMIM RefSeq UniProt Locus q21-q24
general transcription factor IIE, polypeptide 2, beta 34kDa
Identifiers
Symbol GTF2E2
Alt. symbols TF2E2
Entrez HUGO OMIM RefSeq UniProt Locus p12

Transcription factor II E (TFIIE) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.[1]

Transcription Factor II E is encoded by the GTF2E1 and GTF2E2 genes.[2][3][4][5] TFIIE is thought to be involved in DNA melting at the promoter: it contains a zinc ribbon motif that can bind single stranded DNA.[6]

See also

References

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  • Medical Subject Headings (MeSH)


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